Rabbi Simeon ben Lakish of Tiberias (230–270) even asserted that all of the specific names for the angels were brought back by the Jews from Babylonian knowledge. The angels mentioned in the older books of the Hebrew Bible (aka the Tanakh) are without names. In Judaism and Christianity Name and origins Uriel or Auriel (male) / Urielle or Eurielle (female) is also a name assimilated by the Celtic Brittanic culture, because of Saint Urielle (7th century), sister of the Breton king Saint Judicael, who popularised the name. In apocryphal, kabbalistic, and occult works, Uriel/Auriel has been equated (or confused) with Urial, Nuriel, Uryan, Jeremiel, Vretil, Sariel, Suriel, Puruel, Phanuel, Jacob, Azrael, and Raphael. Uriel is also known as a master of knowledge and archangel of wisdom. He is also well known in European esoteric medieval literature. He is well known in the Russian Orthodox tradition (which considers him to be one of the seven major archangels) and recognized in the Anglican Church as the 4th archangel. Iowa State researchers say additional studies are needed to determine if increasing production of SOD1 - possibly through diet or medication - might delay the progression of Alzheimer's disease.Uriel / ˈ j ʊər i ə l/ or Auriel also Oriel ( Hebrew: אוּרִיאֵל ʾŪrīʾēl, " El/ God is my light" or "Light of God" Greek: Οὐριήλ Ouriìl Coptic: ⲟⲩⲣⲓⲏⲗ Ouriyl Italian: Uriele Geʽez and Amharic: ዑራኤል ʿUraʾēl or ዑርኤል ʿUriʾēl) is the name of one of the archangels who is mentioned in the post-exilic rabbinic tradition and in certain Christian traditions. You can pump as much water as possible onto the fire, but once it's spreading out of control, no amount of water is going to stop it." "The disease might begin or progress partly because antioxidants in our brain stop working effectively when tau levels increase," Willette said. Willette says their results provide further evidence of tau's role in the development of Alzheimer's. Until now, it was unknown how SOD1 related to cognition and biomarkers in the brain and cerebrospinal fluid for adults living with the disease. Much of what researchers know about SOD1 and the brain is based on post-mortem brain analysis of patients with Alzheimer's, McLimans said. Of the 287 people in the study, 86 had no cognitive impairment, 135 had mild impairment and 66 had Alzheimer's disease. The researchers analyzed data from adults, ranging in age from 65 to 90, participating in the Alzheimer's Disease Neuroimaging Initiative. The group is the first to identify the correlation between SOD1 and tau proteins in people with varying degrees of Alzheimer's disease. "This study could further the exploration of how nutrition might reduce and prevent neurodegeneration and aging in the brain," Clark said.Īuriel Willette, assistant professor of food science and human nutrition, who oversaw the research Anumantha Kanthasamy, Distinguished Professor and chair of biomedical sciences Vellareddy Anantharam, research associate professor of biomedical sciences Alexandra Plagman, graduate research assistant and Colleen Pappas, postdoctoral research associate, were part of the team working with McLimans and Clark. Clark says the results put researchers another step closer to understanding the importance of antioxidants. Their interest in antioxidants that occur naturally in the body and in the foods we eat led them to look at how SOD1 affects aging. McLimans and Bridget Clark, a former Cyclone Summer Scholar research intern, led the study published online by the journal Antioxidants & Redox Signaling. This bolsters our hypothesis that SOD1 itself isn't detrimental it's just trying to limit the oxidative damage caused by tau." "However, our results show 90 percent of this positive association is negated by tau. graduate and research assistant in food science and human nutrition. "In individuals with Alzheimer's or mild cognitive impairment, SOD1 was related to more gray matter, which is significant for memory," said Kelsey McLimans, a recent Ph.D.
Based on the results, researchers suspect SOD1 is fighting to counteract the damaging effects of tau proteins, but eventually loses the battle. However, an Iowa State University research team found SOD1's protective benefits dramatically weaken when levels of tau proteins - a hallmark of Alzheimer's disease - increase.
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The antioxidant, superoxide dismutase or SOD1, improves cognition by fighting off free radicals that cause oxidative damage in the brain.
AMES, Iowa - New research may explain why an antioxidant that protects the brain is also associated with deterioration in areas susceptible to Alzheimer's disease.